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NADE Polyclonal Antibody
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FIGURE: 1 / 2
NADE Antibody (200-401-CX2) in IHC (P)
Immunohistochemistry of NADE antibody. Tissue: human brain tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: NADE antibody at 2 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: NADE is nuclear and cytoplasmic. Staining: NADE is stained with hematoxylin purple nuclear counterstain.
Product Details
200-401-CX2
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-NADE antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 14 amino acids near the internal region of human NADE.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain expressed X-linked 3; Brain-expressed X-linked protein 3; Brain-expressed X-linked protein 3 homolog; granule cell antiserum positive 27; nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated Cell Death Executor; Protein BEX3; RP13-349O20.1
Gene Aliases: AL033356; Bex; BEX3; DXS6984E; DXWsu67e; Gcap27; HGR74; NADE; NGFRAP1
UniProt ID: (Human) Q00994, (Mouse) Q9WTZ9
Entrez Gene ID: (Human) 27018, (Mouse) 12070
activation of cysteine-type endopeptidase activity involved in apoptotic process
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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