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Invitrogen
NADE Polyclonal Antibody
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Product Details
PA5-20076
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A peptide corresponding to 14 amino acids near the middle of human NADE.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Despite its predicted molecular weight, NADE often migrates at ~23kDa in SDS-PAGE. A suggested positive control is human brain tissue lysate.
PA5-20076 can be used with blocking peptide PEP-0194.
Target Information
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: brain expressed X-linked 3; Brain-expressed X-linked protein 3; Brain-expressed X-linked protein 3 homolog; granule cell antiserum positive 27; nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated Cell Death Executor; Protein BEX3; RP13-349O20.1
Gene Aliases: AL033356; Bex; BEX3; DXS6984E; DXWsu67e; Gcap27; HGR74; NADE; NGFRAP1
UniProt ID: (Human) Q00994, (Mouse) Q9WTZ9
Entrez Gene ID: (Human) 27018, (Mouse) 12070
activation of cysteine-type endopeptidase activity involved in apoptotic process
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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