Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (80%), Pig (95%), Rhesus Monkey (100%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bex; BEX3; brain expressed; Brain-expressed X-linked protein 3; DXS6984E; HGR74; NADE; nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; ovarian granulosa cell protein (13kD); p75NTR-associated cell death executor; Protein BEX3; X-linked 3
Gene Aliases: Bex; BEX3; DXS6984E; HGR74; NADE; NGFRAP1
UniProt ID: (Human) Q00994
Entrez Gene ID: (Human) 27018