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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 19 amino acid peptide near the amino terminus of human NALP13.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||2.5 µg/ml|
|Immunofluorescence (IF)||20 ug/ml|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is K562 cell lysate.
PA5-21028 can be used with blocking peptide PEP-1142.
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CLR19.7, NALP13, NOD14, PAN13; NACHT, leucine rich repeat and PYD containing 13; NACHT, LRR and PYD containing protein 13; NLR family, pyrin domain containing 13; nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
CLR19.7; NALP13; NLRP13; NOD14; PAN13