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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 389 and 678 of Human NBR1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30085 targets NBR1 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-30085 immunogen is recombinant protein fragment corresponding to a region within amino acids 389 and 678 of Human NBR1.
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
1A1-3B; B-box protein; cell migration-inducing gene 19 protein; chromosome 17; M17S2; membrane component; membrane component chromosome 17 surface marker 2; membrane component chromosome 17 surface marker 2 homolog; membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125); migration-inducing protein 19; neighbor of BRCA1 gene 1; neighbor of BRCA1 gene 1 protein; next to BRCA1 ge; next to BRCA1 gene 1 protein; next to the Brca1; surface marker 2 (ovarian carcinoma antigen CA125)
1A1-3B; 1A13B; IAI3B; KIAA0049; M17S2; MIG19; mKIAA0049; NBR1