Immunogen sequence: YSTPRLPAAL EQVRLQKQVD KNFLKAEKQR LRAEKKQRKA EVKELKKQLK LHRKIHLWNS IHGLQSPKSP LGRPESLLQS NTLMLPLQPC TSVMPMLS
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-box protein; Cell migration-inducing gene 19 protein; Membrane component chromosome 17 surface marker 2; membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125); migration-inducing protein 19; neighbor of BRCA1 gene 1; Neighbor of BRCA1 gene 1 protein; Next to BRCA1 gene 1 protein; Protein 1A1-3B
Gene Aliases: 1A1-3B; 1A13B; IAI3B; KIAA0049; M17S2; MIG19; NBR1
UniProt ID: (Human) Q14596
Entrez Gene ID: (Human) 4077