Recommended positive controls: K562.
Predicted reactivity: Mouse (98%), Rat (99%), Xenopus laevis (84%), Pig (97%), Sheep (98%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
NCK1 is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytoplasmic protein NCK1; melanoma NCK protein; MGC12668; NCK adaptor protein 1; NCK tyrosine kinase; Nck-1; non-catalytic region of tyrosine kinase; SH2/SH3 adaptor protein NCK-alpha
Gene Aliases: NCK; nck-1; NCK1; NCKalpha
UniProt ID: (Human) P16333
Entrez Gene ID: (Human) 4690