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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||A synthetic peptide from the human SMRT protein corresponding to amino acids 80-92 (QELHLRPESHSYL).|
|Storage buffer||PBS, pH 7.4|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-23286 detects SMRT in Human samples.
PA1-23286 has been successfully used in Immunoprecipitation and Western Blot procedures.
PA1-23286 immunogen corresponds to a synthetic peptide from the human SMRT protein corresponding to amino acids 80-92 (QELHLRPESHSYL).
Clone G9 recognizes the Silencing Mediator for Retinoid and Thyroid receptors (SMRT) gene product, a 168 kDa nuclear protein. Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CTG repeat protein 26; silencing mediator for retinoid and thyroid hormone receptors; Silencing Mediator of Retinoic Acid & Thyroid Hormone Receptor; T3 receptor-associating factor; thyroid-, retinoic-acid-receptor-associated corepressor
CTG26; N-CoR2; NCOR2; SMAP270; SMRT; SMRTE; SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1