|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||A synthetic peptide from the human SMRT protein corresponding to amino acids 80-92 (QELHLRPESHSYL).|
|Storage buffer||PBS, pH 7.4|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-23286 detects SMRT in Human samples.
PA1-23286 has been successfully used in Immunoprecipitation and Western Blot procedures.
PA1-23286 immunogen corresponds to a synthetic peptide from the human SMRT protein corresponding to amino acids 80-92 (QELHLRPESHSYL).
Clone G9 recognizes the Silencing Mediator for Retinoid and Thyroid receptors (SMRT) gene product, a 168 kDa nuclear protein. Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CTG repeat protein 26; N-CoR2; Nuclear receptor corepressor 2; silencing mediator for retinoid and thyroid hormone receptors; Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor; Silencing mediator of retinoic acid and thyroid hormone receptor; SMAP270; SMRT; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TRAC
Gene Aliases: CTG26; N-CoR2; NCOR2; SMAP270; SMRT; SMRTE; SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1
UniProt ID: (Human) Q9Y618
Entrez Gene ID: (Human) 9612
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