Product References
PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation.
Cell death & disease
Ren L,Meng L,Gao J,Lu M,Guo C,Li Y,Rong Z,Ye Y
Fri Jan 20 00:00:00 EST 2023
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Signal transduction and targeted therapy
Ma B,Ju A,Zhang S,An Q,Xu S,Liu J,Yu L,Fu Y,Luo Y
Fri Jun 16 00:00:00 EDT 2023
Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells.
Proteome science
Xu X,Liu Y,Luan J,Liu R,Wang Y,Liu Y,Xu A,Zhou B,Han F,Shang W
Wed Sep 07 00:00:00 EDT 2022
Two independent respiratory chains adapt OXPHOS performance to glycolytic switch.
Cell metabolism
Fernández-Vizarra E,López-Calcerrada S,Sierra-Magro A,Pérez-Pérez R,Formosa LE,Hock DH,Illescas M,Peñas A,Brischigliaro M,Ding S,Fearnley IM,Tzoulis C,Pitceathly RDS,Arenas J,Martín MA,Stroud DA,Zeviani M,Ryan MT,Ugalde C
Tue Nov 01 00:00:00 EDT 2022
Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats.
Journal of cancer prevention
Hahm ER,Singh SV
Wed Mar 30 00:00:00 EDT 2022
Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans.
Redox biology
Hermeling JC,Herholz M,Baumann L,Cores EC,Zečić A,Hoppe T,Riemer J,Trifunovic A
Thu Dec 01 00:00:00 EST 2022
Applying Sodium Carbonate Extraction Mass Spectrometry to Investigate Defects in the Mitochondrial Respiratory Chain.
Frontiers in cell and developmental biology
Robinson DRL,Hock DH,Muellner-Wong L,Kugapreethan R,Reljic B,Surgenor EE,Rodrigues CHM,Caruana NJ,Stroud DA
Sat Mar 19 00:00:00 EDT 2022
GABA regulates IL-1β production in macrophages.
Cell reports
Fu J,Han Z,Wu Z,Xia Y,Yang G,Yin Y,Ren W
Tue Dec 06 00:00:00 EST 2022
CLPP deficiency ameliorates neurodegeneration caused by impaired mitochondrial protein synthesis.
Brain : a journal of neurology
Rumyantseva A,Popovic M,Trifunovic A
Tue Mar 29 00:00:00 EDT 2022
The FoxQ1 transcription factor is a novel regulator of electron transport chain complex I subunits in human breast cancer cells.
Molecular carcinogenesis
Kim SH,Singh SV
Tue Mar 01 00:00:00 EST 2022
Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.
Signal transduction and targeted therapy
Xue W,Li X,Li W,Wang Y,Jiang C,Zhou L,Gao J,Yu Y,Shen Y,Xu Q
Fri Feb 04 00:00:00 EST 2022
Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.
Signal transduction and targeted therapy
Xue W,Li X,Li W,Wang Y,Jiang C,Zhou L,Gao J,Yu Y,Shen Y,Xu Q
Fri Feb 04 00:00:00 EST 2022
Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells.
Developmental cell
Ojha R,Tantray I,Rimal S,Mitra S,Cheshier S,Lu B
Mon Jan 24 00:00:00 EST 2022
Metabolism-Based Molecular Subtyping Endows Effective Ketogenic Therapy in p53-Mutant Colon Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tang M,Xu H,Huang H,Kuang H,Wang C,Li Q,Zhang X,Ge Y,Song M,Zhang X,Wang Z,Ma C,Kang J,Zhang W,Wang Y,Zhang B,Zhang X,Chen Y,Cong M,Melino G,Wang X,Zhou F,Sun Q,Shi H
Sat Oct 01 00:00:00 EDT 2022
Mitochondrial dysfunction induces radioresistance in colorectal cancer by activating [Ca2+]m-PDP1-PDH-histone acetylation retrograde signaling.
Cell death & disease
Shi Y,Wang Y,Jiang H,Sun X,Xu H,Wei X,Wei Y,Xiao G,Song Z,Zhou F
Mon Sep 06 00:00:00 EDT 2021
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I.
Theranostics
Jiang L,Yin X,Chen YH,Chen Y,Jiang W,Zheng H,Huang FQ,Liu B,Zhou W,Qi LW,Li J
Mon Aug 16 00:00:00 EDT 2021
Effects of glucose metabolism pathways on nuclear and cytoplasmic maturation of pig oocytes.
Scientific reports
Wen J,Wang GL,Yuan HJ,Zhang J,Xie HL,Gong S,Han X,Tan JH
Mon Feb 17 00:00:00 EST 2020
Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway.
American journal of translational research
Chen L,Peng J,Wang Y,Jiang H,Wang W,Dai J,Tang M,Wei Y,Kuang H,Xu G,Xu H,Zhou F
Mon Sep 28 00:00:00 EDT 2020
A salvage pathway maintains highly functional respiratory complex I.
Nature communications
Szczepanowska K,Senft K,Heidler J,Herholz M,Kukat A,Höhne MN,Hofsetz E,Becker C,Kaspar S,Giese H,Zwicker K,Guerrero-Castillo S,Baumann L,Kauppila J,Rumyantseva A,Müller S,Frese CK,Brandt U,Riemer J,Wittig I,Trifunovic A
Thu Apr 02 00:00:00 EDT 2020
Solvent-Induced Protein Precipitation for Drug Target Discovery on the Proteomic Scale.
Analytical chemistry
Zhang X,Wang Q,Li Y,Ruan C,Wang S,Hu L,Ye M
Tue Jan 07 00:00:00 EST 2020
Novel MT-ND Gene Variants Causing Adult-Onset Mitochondrial Disease and Isolated Complex I Deficiency.
Frontiers in genetics
Ng YS,Thompson K,Loher D,Hopton S,Falkous G,Hardy SA,Schaefer AM,Shaunak S,Roberts ME,Lilleker JB,Taylor RW
Sun Jan 10 00:00:00 EST 2021
Bi-allelic pathogenic variants in NDUFC2 cause early-onset Leigh syndrome and stalled biogenesis of complex I.
EMBO molecular medicine
Alahmad A,Nasca A,Heidler J,Thompson K,Oláhová M,Legati A,Lamantea E,Meisterknecht J,Spagnolo M,He L,Alameer S,Hakami F,Almehdar A,Ardissone A,Alston CL,McFarland R,Wittig I,Ghezzi D,Taylor RW
Fri Nov 06 00:00:00 EST 2020
The Mitochondrial Acyl-carrier Protein Interaction Network Highlights Important Roles for LYRM Family Members in Complex I and Mitoribosome Assembly.
Molecular & cellular proteomics : MCP
Dibley MG,Formosa LE,Lyu B,Reljic B,McGann D,Muellner-Wong L,Kraus F,Sharpe AJ,Stroud DA,Ryan MT
Wed Jan 01 00:00:00 EST 2020
In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer.
Nature
Momcilovic M,Jones A,Bailey ST,Waldmann CM,Li R,Lee JT,Abdelhady G,Gomez A,Holloway T,Schmid E,Stout D,Fishbein MC,Stiles L,Dabir DV,Dubinett SM,Christofk H,Shirihai O,Koehler CM,Sadeghi S,Shackelford DB
Fri Nov 01 00:00:00 EDT 2019
CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis.
EMBO reports
Becker C,Kukat A,Szczepanowska K,Hermans S,Senft K,Brandscheid CP,Maiti P,Trifunovic A
Tue May 01 00:00:00 EDT 2018
CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis.
EMBO reports
Becker C,Kukat A,Szczepanowska K,Hermans S,Senft K,Brandscheid CP,Maiti P,Trifunovic A
Tue May 01 00:00:00 EDT 2018
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Cancer science
Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y
Sat Dec 01 00:00:00 EST 2018
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Cancer science
Liu L,Sun Y,Zhao Y,Wang Q,Guo H,Guo R,Liu Y,Fu S,Zhang L,Li Y,Meng Y
Sat Dec 01 00:00:00 EST 2018
Glucose metabolism during in vitro maturation of mouse oocytes: An study using RNA interference.
Journal of cellular physiology
Xie HL,Zhu S,Zhang J,Wen J,Yuan HJ,Pan LZ,Luo MJ,Tan JH
Sat Sep 01 00:00:00 EDT 2018
Glucose metabolism during in vitro maturation of mouse oocytes: An study using RNA interference.
Journal of cellular physiology
Xie HL,Zhu S,Zhang J,Wen J,Yuan HJ,Pan LZ,Luo MJ,Tan JH
Sat Sep 01 00:00:00 EDT 2018
Quantitative temporal analysis of protein dynamics in cardiac remodeling.
Journal of molecular and cellular cardiology
McClatchy DB,Ma Y,Liem DA,Ng DCM,Ping P,Yates JR
Wed Aug 01 00:00:00 EDT 2018
Quantitative temporal analysis of protein dynamics in cardiac remodeling.
Journal of molecular and cellular cardiology
McClatchy DB,Ma Y,Liem DA,Ng DCM,Ping P,Yates JR
Wed Aug 01 00:00:00 EDT 2018
Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.
Molecular cell
Kang Y,Stroud DA,Baker MJ,De Souza DP,Frazier AE,Liem M,Tull D,Mathivanan S,McConville MJ,Thorburn DR,Ryan MT,Stojanovski D
Thu Aug 03 00:00:00 EDT 2017
Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.
Molecular cell
Kang Y,Stroud DA,Baker MJ,De Souza DP,Frazier AE,Liem M,Tull D,Mathivanan S,McConville MJ,Thorburn DR,Ryan MT,Stojanovski D
Thu Aug 03 00:00:00 EDT 2017
Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Nature
Stroud DA,Surgenor EE,Formosa LE,Reljic B,Frazier AE,Dibley MG,Osellame LD,Stait T,Beilharz TH,Thorburn DR,Salim A,Ryan MT
Thu Oct 06 00:00:00 EDT 2016
Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Nature
Stroud DA,Surgenor EE,Formosa LE,Reljic B,Frazier AE,Dibley MG,Osellame LD,Stait T,Beilharz TH,Thorburn DR,Salim A,Ryan MT
Thu Oct 06 00:00:00 EDT 2016
Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability.
eLife
Kang Y,Baker MJ,Liem M,Louber J,McKenzie M,Atukorala I,Ang CS,Keerthikumar S,Mathivanan S,Stojanovski D
Wed Aug 24 00:00:00 EDT 2016
Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability.
eLife
Kang Y,Baker MJ,Liem M,Louber J,McKenzie M,Atukorala I,Ang CS,Keerthikumar S,Mathivanan S,Stojanovski D
Wed Aug 24 00:00:00 EDT 2016
Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway.
Scientific reports
Tang H,Li J,Liu X,Wang G,Luo M,Deng H
Tue Jun 21 00:00:00 EDT 2016
Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway.
Scientific reports
Tang H,Li J,Liu X,Wang G,Luo M,Deng H
Tue Jun 21 00:00:00 EDT 2016
A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.
Cell reports
Pryde KR,Taanman JW,Schapira AH
Tue Dec 06 00:00:00 EST 2016
A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.
Cell reports
Pryde KR,Taanman JW,Schapira AH
Tue Dec 06 00:00:00 EST 2016
Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling.
Human molecular genetics
Lopes Costa A,Le Bachelier C,Mathieu L,Rotig A,Boneh A,De Lonlay P,Tarnopolsky MA,Thorburn DR,Bastin J,Djouadi F
Tue Apr 15 00:00:00 EDT 2014
Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling.
Human molecular genetics
Lopes Costa A,Le Bachelier C,Mathieu L,Rotig A,Boneh A,De Lonlay P,Tarnopolsky MA,Thorburn DR,Bastin J,Djouadi F
Tue Apr 15 00:00:00 EDT 2014
GSH monoethyl ester rescues mitochondrial defects in cystic fibrosis models.
Human molecular genetics
Kelly-Aubert M,Trudel S,Fritsch J,Nguyen-Khoa T,Baudouin-Legros M,Moriceau S,Jeanson L,Djouadi F,Matar C,Conti M,Ollero M,Brouillard F,Edelman A
Fri Jul 15 00:00:00 EDT 2011
GSH monoethyl ester rescues mitochondrial defects in cystic fibrosis models.
Human molecular genetics
Kelly-Aubert M,Trudel S,Fritsch J,Nguyen-Khoa T,Baudouin-Legros M,Moriceau S,Jeanson L,Djouadi F,Matar C,Conti M,Ollero M,Brouillard F,Edelman A
Fri Jul 15 00:00:00 EDT 2011
Complex I specific increase in superoxide formation and respiration rate by PrP-null mouse brain mitochondria.
Journal of neurochemistry
Paterson AW,Curtis JC,Macleod NK
Tue Apr 01 00:00:00 EDT 2008
Complex I specific increase in superoxide formation and respiration rate by PrP-null mouse brain mitochondria.
Journal of neurochemistry
Paterson AW,Curtis JC,Macleod NK
Tue Apr 01 00:00:00 EDT 2008