Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:2,000-1:12,000 | View 7 publications 7 publications |
Immunohistochemistry (IHC) |
- | View 3 publications 3 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
ChIP assay (ChIP) |
Assay-dependent | View 2 publications 2 publications |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
NELFE Fusion Protein Ag1186 (1-333 aa encoded by BC011600) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
10705-1-AP is obtained by immunizing animals with full-length RDBP of human origin.
Immunogen sequence: MLVIPPGLS EEEEALQKKF NKLKKKKKAL LALKKQSSSS TTSQGGVKRS LSEQPVMDTA TATEQAKQLV KSGAISAIKA ETKNSGFKRS RTLEGKLKDP EKGPVPTFQP FQRSISADDD LQESSRRPQR KSLYESDRLR ELGPDGEEAE GPGAGDGPPR SFDWGYEERS GAHSSASPPR SRSRDRSHER NRDRDREGPF RRSDSFPERR APRKGNTLYV YGEDMTPTLL RGAFSPFGNI IDLSMDPPRN CAFVTYEKME SADQAVAELN GTQVESVQLK VNIARKQPML DAATGKSVWG SLAVQNSPKG CHRDKRTQIV YSDDVYKENL VDGF (1-333 aa encoded by BC011600)
RDBP is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: major histocompatibility complex gene RD; Negative elongation factor E; negative elongation factor polypeptide E; NELF E; NELF-E; nuclear protein; RD RNA binding protein; RD RNA-binding protein; RNA-binding protein RD
Gene Aliases: D17H6S45; D6S45; NELF-E; NELFE; RD; RDBP; RDP
UniProt ID: (Human) P18615, (Mouse) P19426
Entrez Gene ID: (Human) 7936, (Mouse) 27632, (Rat) 294258
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