Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
NET1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 2
NET1 Antibody (PA5-102391) in WB
Western blot analysis of NET1 in extracts from various samples. Samples were incubated with NET1 polyclonal antibody (Product # PA5-102391). Lane 1: Hepg2 cells (serum starvation treatment), blocked with antigen-specific peptides; Lane 2: Hepg2 cells (serum starvation treatment); Lane 3: Hela cells (heat-shock treatment).
Product Details
PA5-102391
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NET1(Accession Q7Z628), corresponding to amino acid residues A563-V596.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total NET1.
Target Information
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: guanine nucleotide regulatory protein (oncogene); Net1 homolog; neuroepithelial cell transforming gene 1; Neuroepithelial cell-transforming gene 1 protein; neuroepithelioma transforming gene 1; p65 Net1 proto-oncogene protein; Proto-oncogene p65 Net1; Rho guanine nucleotide exchange factor (GEF) 8; Rho guanine nucleotide exchange factor 8; RP11-116G8.1; small GTP-binding protein regulator
Gene Aliases: ARHGEF8; mNET1; NET1; NET1A
UniProt ID: (Human) Q7Z628, (Mouse) Q9Z206
Entrez Gene ID: (Human) 10276, (Mouse) 56349, (Rat) 307098
regulation of cell growth
signal transduction
regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
myoblast migration
cellular response to hydrogen peroxide
cellular response to ionizing radiation
positive regulation of substrate adhesion-dependent cell spreading
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support