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Antibody detects endogenous levels of total NETO2.
NETO2 is a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis.This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis. Alternatively spliced transcript variants have been observed, but they have not been fully characterized.
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Protein Aliases: Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2; FLJ10430; FLJ14724; FLJ90456; NEOT2FLJ14724; neuropilin (NRP) and tolloid (TLL)-like 2; Neuropilin and tolloid-like protein 2
Gene Aliases: 5530601C23Rik; AI854825; BTCL2; NEOT2; NETO2; UNQ1926/PRO4401
UniProt ID: (Human) Q8NC67, (Mouse) Q8BNJ6
Entrez Gene ID: (Human) 81831, (Mouse) 74513
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