Immunogen sequence: VFGRGETLGP APRAGGTMKS AEEEHYGYAS SNVSPALPLP TAHSTLPAPC HNLQTSTPGI IPPADHPSGY GAALDGGPAG YFLSSGHTRP DGAPALESPR IEITSCLGLY HNNNQFFHDV EVEDVLPSSK RSPSTATLSL PSLEAYRDPS CLSPASSLSS RSCNSEASSY ESNYSYPYAS PQTSPWQSPC VSPKTTDPEE GFPRGLGACT LLGSPRHSPS TSPRASVTEE SWLGARSSRP ASPCNKRKYS LNGRQPPYSP HHSPTPSPHG SPRVSVTDDS W; Positive Samples: Jurkat, U-87MG, K-562, Mouse spleen; Cellular Location: Cytoplasm, Nucleus
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that coordinate the immune response. NFATc is the cytosolic component of NFAT and encoded by a separate gene. Expression of NFATc activates the interleukin (IL-2) promoter in non-T lymphocytes and is required for IL-2 gene expression.
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Protein Aliases: NF-ATc; NF-ATc1; NFAT transcription complex cytosolic component; nuclear factor of activated T-cells 'c'; Nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NF-ATc
Gene Aliases: 2210017P03Rik; AI449492; AV076380; NF-ATC; NF-ATc1.2; NFAT2; NFATC; NFATC1; Nfatcb
UniProt ID: (Human) O95644
Molecular Function: transcription factor