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NFATC4 Antibody (PA5-85559) in WB
Western blot analysis of NFATC4 in A) 293T whole cell lysate B. whole cell lysate of human NFATC4-transfected 293T cells using NFATC4 polyclonal antibody (Product # PA5-85559) using 30 µg of sample at a dilution of 1:10000. Prior to incubation with primary antibody, the sample was separated on 7.5% SDS-PAGE.
Product Details
PA5-85559
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human NFATC4.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792699
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (91%), Rat (91%).
Positive Control: NFATC4-transfected 293T cells.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein is an adapter or scaffold protein, which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NF-AT3; NF-ATc4; Nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3
Gene Aliases: NF-AT3; NF-ATC4; NFAT3; NFATC4
UniProt ID: (Human) Q14934
Entrez Gene ID: (Human) 4776
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription coactivator activity
protein binding
transcription factor binding
peroxisome proliferator activated receptor binding
Rel homology transcription factor
patterning of blood vessels
transcription from RNA polymerase II promoter
inflammatory response
heart development
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of Wnt signaling pathway
negative regulation of protein binding
positive regulation of tumor necrosis factor production
calcineurin-NFAT signaling cascade
cellular response to UV
negative regulation of chromatin binding
cellular respiration
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
smooth muscle cell differentiation
muscle cell development
cellular response to lithium ion
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of synapse maturation
positive regulation of apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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