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Invitrogen
NFATC4 Polyclonal Antibody
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FIGURE: 1 / 1
NFATC4 Antibody (PA5-85559) in WB
NFATC4 Polyclonal Antibody detects NFATC4 protein by western blot analysis. A. 30 µg 293T whole cell lysate/extract. B. 30 µg whole cell lysate/extract of human NFATC4-transfected 293T cells.7.5 % SDS-PAGE. NFATC4 Polyclonal Antibody (Product # PA5-85559) dilution: 1:10,000.
Product Details
PA5-85559
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human NFATC4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (91%), Rat (91%).
Positive Control: NFATC4-transfected 293T cells.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein is an adapter or scaffold protein, which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NF-AT3; NF-ATc4; Nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3; transcription factor; unnamed protein product
Gene Aliases: NF-AT3; NF-ATC4; NFAT3; NFATC4
UniProt ID: (Human) Q14934
Entrez Gene ID: (Human) 4776
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
patterning of blood vessels
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
inflammatory response
heart development
long-term memory
intrinsic apoptotic signaling pathway in response to DNA damage
cell differentiation
negative regulation of Wnt signaling pathway
brain-derived neurotrophic factor receptor signaling pathway
positive regulation of tumor necrosis factor production
calcineurin-NFAT signaling cascade
cellular response to UV
vascular smooth muscle cell differentiation
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
cellular respiration
positive regulation of transcription from RNA polymerase II promoter
dendrite morphogenesis
negative regulation of dendrite morphogenesis
neuron apoptotic process
synapse maturation
long-term synaptic potentiation
cellular response to lithium ion
vascular smooth muscle cell development
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of synapse maturation
positive regulation of apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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