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Proteintech
NKIRAS2 Polyclonal Antibody
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Product Details
10174-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NKIRAS2 Fusion Protein Ag0221 (1-191 aa encoded by BC007450)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MGKSCKVVV CGQASVGKTS ILEQLLYGNH VVGSEMIETQ EDIYVGSIET DRGVREQVRF YDTRGLRDGA ELPRHCFSCT DGYVLVYSTD SRESFQRVEL LKKEIDKSKD KKEVTIVVLG NKCDLQEQRR VDPDVAQHWA KSEKVKLWEV SVADRRSLLE PFVYLASKMT QPQSKSAFPL SRKNKGSGSL DG (1-191 aa encoded by BC007450)
Target Information
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; unnamed protein product
Gene Aliases: kappaB-Ras2; KBRAS2; NKIRAS2
UniProt ID: (Human) Q9NYR9
Entrez Gene ID: (Human) 28511
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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