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Invitrogen
NLGN3 Polyclonal Antibody
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FIGURE: 1 / 4
NLGN3 Antibody (PA5-78508) in ICC/IF
NLGN3 Polyclonal Antibody detects Neuroligin 3 protein by immunofluorescent analysis. Sample: DIV14 rat E18 primary cortical neurons were fixed in 4% paraformaldehyde at RT for 15 min. Green: Neuroligin 3 protein stained by NLGN3 Polyclonal Antibody (Product # PA5-78508) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta-3 Tubulin Polyclonal Antibody [GT1338]diluted at 1:500. Blue: Fluoroshield with DAPI .
Product Details
PA5-78508
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human Neuroligin 3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.41 mg/mL
Amount
141 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: mouse brain, rat brain, SK-N-SH
Predicted Reactivity: Japanese Medaka (80%), Xenopus laevis (81%), Chicken (86%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ASPGX1; AUTSX1; Gliotactin homolog; neuroligin 3 protein; Neuroligin-3; unnamed protein product
Gene Aliases: A230085M13Rik; HNL3; KIAA1480; NL3; NLGN3
UniProt ID: (Human) Q9NZ94, (Mouse) Q8BYM5, (Rat) Q62889
Entrez Gene ID: (Human) 54413, (Mouse) 245537, (Rat) 171297
regulation of respiratory gaseous exchange by neurological system process
receptor-mediated endocytosis
cell adhesion
neuron cell-cell adhesion
chemical synaptic transmission
synapse assembly
learning
adult behavior
social behavior
synaptic vesicle endocytosis
axon extension
modulation of synaptic transmission
synapse organization
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
rhythmic synaptic transmission
inhibitory postsynaptic potential
vocalization behavior
postsynaptic membrane assembly
presynaptic membrane assembly
presynapse assembly
positive regulation of glutamate receptor signaling pathway
positive regulation of excitatory postsynaptic potential
visual learning
oligodendrocyte differentiation
regulation of synaptic transmission, glutamatergic
excitatory postsynaptic potential
positive regulation of dendritic spine development
regulation of dendritic spine morphogenesis
positive regulation of inhibitory postsynaptic potential
regulation of long-term synaptic potentiation
positive regulation of protein localization to synapse
regulation of N-methyl-D-aspartate selective glutamate receptor activity
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
regulation of terminal button organization
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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