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Product Details
12923-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NME5 Fusion Protein Ag3610 (1-212 aa encoded by BC026182)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MEISMPPPQ IYVEKTLAII KPDIVDKEEE IQDIILRSGF TIVQRRKLRL SPEQCSNFYV EKYGKMFFPN LTAYMSSGPL VAMILARHKA ISYWLELLGP NNSLVAKETH PDSLRAIYGT DDLRNALHGS NDFAAAEREI RFMFPEVIVE PIPIGQAAKD YLNLHIMPTL LEGLTELCKQ KPADPLIWLA DWLLKNNPNK PKLCHHPIVE EPY (1-212 aa encoded by BC026182)
Target Information
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: expressed in non-metastatic cells 5; Inhibitor of p53-induced apoptosis-beta; IPIA-beta; NDK-H 5; NDP kinase homolog 5; nm23-H5; nm23-M5; NME/NM23 family member 5; non-metastatic cells 5 protein expressed in; non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nucleoside diphosphate kinase homolog 5; radial spoke 23 homolog; Rsph23; Testis-specific nm23 homolog
Gene Aliases: 1700019D05Rik; NM23-H5; Nm23-M5; NM23H5; NME5; RSPH23
UniProt ID: (Human) P56597, (Mouse) Q99MH5
Entrez Gene ID: (Human) 8382, (Mouse) 75533, (Rat) 688903
Molecular Function:
kinase
nucleotide kinase
transferase
metabolite interconversion enzyme
epithelial cilium movement
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
spermatogenesis
spermatid development
nucleoside metabolic process
ventricular system development
cilium assembly
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
response to reactive oxygen species
multicellular organism development
cell differentiation
spermatid differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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