This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.
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Protein Aliases: Glycylpeptide N-tetradecanoyltransferase 2; glycylpeptide N-tetradecanoyltransferase 2 variant 3; glycylpeptide N-tetradecanoyltransferase 2 variant 4; Myristoyl-CoA:protein N-myristoyltransferase 2; N-myristoyltransferase 2-like; NMT 2; Peptide N-myristoyltransferase 2; Type II N-myristoyltransferase
Gene Aliases: A930001K02Rik; AI605445; AU044698; BOS_12847; fb40e03; hNMT-2; NMT 2; NMT2; wu:fb40e03
Molecular Function: transferase