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Proteintech
NONO Polyclonal Antibody
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Product Details
11058-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Bovine,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NONO Fusion Protein Ag1512 (124-471 aa encoded by BC010049)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Amount
48 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IAKVELDNM PLRGKQLRVR FACHSASLTV RNLPQYVSNE LLEEAFSVFG QVERAVVIVD DRGRPSGKGI VEFSGKPAAR KALDRCSEGS FLLTTFPRPV TVEPMDQLDD EEGLPEKLVI KNQQFHKERE QPPRFAQPGS FEYEYAMRWK ALIEMEKQQQ DQVDRNIKEA REKLEMEMEA ARHEHQVMLM RQDLMRRQEE LRRMEELHNQ EVQKRKQLEL RQEEERRRRE EEMRRQQEEM MRRQQEGFKG TFPDAREQEI RMGQMAMGGA MGINNRGAMP PAPVPAGTPA PPGPATMMPD GTLGLTPPTT ERFGQAATME GIGAIGGTPP AFNRAAPGAE FAPNKRRRY (124-471 aa encoded by BC010049)
Target Information
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 54 kDa nuclear RNA- and DNA-binding protein; 55 kDa nuclear protein; DNA-binding p52/p100 complex, 52 kDa subunit; HGNC:7871; NMT-1; NMT55; non-POU domain-containing octamer (ATGCAAAT) binding protein; Non-POU domain-containing octamer-binding protein; non-POU-domain-containing; non-POU-domain-containing, octamer-binding protein; NONO; NonO protein; p54(nrb); protein phosphatase 1, regulatory subunit 114; sequence is expressed in human Tera-2 clone 13 (embryonal carcinoma) cells. The sequence may contain mismatches (one strand sequenced only once). 97% identical in 320 bp overlap with human 54 kDA prot; ORF; unnamed protein product
Gene Aliases: AA407051; AV149256; MRXS34; NMT55; nonA; NONO; NRB54; P54; P54NRB; PPP1R114
UniProt ID: (Human) Q15233, (Mouse) Q99K48, (Rat) Q5FVM4
Entrez Gene ID: (Human) 4841, (Mouse) 53610, (Rat) 317259
activation of innate immune response
immune system process
DNA repair
DNA recombination
regulation of transcription, DNA-templated
mRNA processing
cellular response to DNA damage stimulus
circadian rhythm
RNA splicing
regulation of circadian rhythm
negative regulation of apoptotic process
innate immune response
negative regulation of transcription, DNA-templated
rhythmic process
cellular response to hypoxia
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
cellular response to angiotensin
transcription, DNA-templated
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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