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Proteintech
NPC2 Polyclonal Antibody
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Product Details
19888-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NPC2 Fusion Protein Ag13719 (1-151 aa encoded by BC002532)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRFLAATFL LLALSTAAQA EPVQFKDCGS VDGVIKEVNV SPCPTQPCQL SKGQSYSVNV TFTSNIQSKS SKAVVHGILM GVPVPFPIPE PDGCKSGINC PIQKDKTYSY LNKLPVKSEY PSIKLVVEWQ LQDDKNQSLF CWEIPVQIVS HL (1-151 aa encoded by BC002532)
Target Information
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymal protein 1; Epididymal secretory protein E1; epididymis secretory sperm binding protein; He1; Human epididymis-specific protein 1; mE1; MGC1333; Niemann Pick type C2 protein homolog; Niemann-Pick disease type C2 protein; NP-C2; NPC intracellular cholesterol transporter 2; tissue-specific secretory protein; unnamed protein product
Gene Aliases: 2700012J19Rik; AA408070; AU045843; EDDM1; HE1; NPC2
UniProt ID: (Human) P61916, (Mouse) Q9Z0J0
Entrez Gene ID: (Human) 10577, (Mouse) 67963
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
cholesterol transport
intracellular sterol transport
intracellular cholesterol transport
cholesterol efflux
cholesterol homeostasis
lipid transport
response to virus
gene expression
cholesterol storage
phospholipid transport
sterol transport
sterol metabolic process
regulation of isoprenoid metabolic process
glycolipid transport
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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