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Invitrogen
NPC2 Polyclonal Antibody
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Product Details
PA5-51242
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein of human NPC2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total NPC2 protein.
Target Information
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymal protein 1; Epididymal secretory protein E1; He1; Human epididymis-specific protein 1; mE1; MGC1333; Niemann Pick type C2 protein homolog; Niemann-Pick disease type C2 protein; Niemann-Pick disease, type C2; NP-C2; NPC intracellular cholesterol transporter 2; tissue-specific secretory protein
Gene Aliases: 2700012J19Rik; AA408070; AU045843; EDDM1; HE1; NPC2
UniProt ID: (Human) P61916, (Mouse) Q9Z0J0
Entrez Gene ID: (Human) 10577, (Mouse) 67963
cholesterol metabolic process
response to virus
phospholipid transport
regulation of isoprenoid metabolic process
cholesterol transport
intracellular sterol transport
intracellular cholesterol transport
cholesterol efflux
cholesterol homeostasis
glycolipid transport
lipid metabolic process
steroid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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