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Proteintech
NPPC Polyclonal Antibody
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FIGURE: 1 / 3
NPPC Antibody (29352-1-AP) in IHC (P)
Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse heart tissue using NPPC antibody (29352-1-AP) at dilution of 1:200 and CoraLite 488-Conjugated Goat Anti-Rabbit IgG (H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
29352-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (aa 74-126).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.55 mg/mL
Amount
82.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: natriuretic peptide precursor C; natriuretic peptide precursor type C; NPPC; unnamed protein product
Gene Aliases: CNP; CNP2; lbab
UniProt ID: (Human) P23582, (Rat) P55207, (Mouse) Q61839
Entrez Gene ID: (Human) 4880, (Rat) 114593, (Mouse) 18159
angiogenesis
ovarian follicle development
cumulus cell differentiation
response to hypoxia
blood vessel remodeling
response to ischemia
growth plate cartilage chondrocyte differentiation
growth plate cartilage chondrocyte proliferation
cGMP biosynthetic process
protein folding
cellular calcium ion homeostasis
receptor guanylyl cyclase signaling pathway
negative regulation of cell proliferation
response to xenobiotic stimulus
response to wounding
post-embryonic development
negative regulation of collagen biosynthetic process
gastric emptying
response to decreased oxygen levels
regulation of multicellular organism growth
negative regulation of neuron apoptotic process
response to ethanol
positive regulation of osteoblast differentiation
animal organ development
oocyte development
regulation of smooth muscle cell proliferation
response to axon injury
chromosome organization
negative regulation of meiotic cell cycle
c-di-GMP signaling
multicellular organismal locomotion
response to oxygen-glucose deprivation
negative regulation of oocyte maturation
meiotic cell cycle process involved in oocyte maturation
cellular response to glycoprotein
negative regulation of DNA biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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