Immunogen sequence: PEFEKFSMEVK SSVEKQGLNM EDYVNMFVEG FHDAILLYVL ALHEVLRAGY SKKDGGKIIQ QTWNRTFEGI AGQVSIDANG DRYGDFSVIA MTDVEAGTQE VIGDYFGKEG RFEMRPNVKY PWGPLKLRID ENRIVEHTNS SPCK
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
ANPC is a receptor for atrial natriuretic peptide. It does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.
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Protein Aliases: ANP-C; ANPRC; Atrial natriuretic peptide C-type receptor; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; guanylate cyclase C; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); NPR-C
Gene Aliases: ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPR3; NPRC
UniProt ID: (Human) P17342
Entrez Gene ID: (Human) 4883