Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 2 publications 2 publications |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 2 publications 2 publications |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
ChIP assay (ChIP) |
Assay-dependent | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
NR1D1 Fusion Protein Ag5964 (1-350 aa encoded by BC056148) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.26 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
This is a rabbit polyclonal antibody raised against the N terminus of human NR1D1.
Immunogen sequence: MTTLDSNNN TGGVITYIGS SGSSPSRTSP ESLYSDNSNG SFQSLTQGCP TYFPPSPTGS LTQDPARSFG SIPPSLSDDG SPSSSSSSSS SSSSFYNGSP PGSLQVAMED SSRVSPSKST SNITKLNGMV LLCKVCGDVA SGFHYGVHAC EGCKGFFRRS IQQNIQYKRC LKNENCSIVR INRNRCQQCR FKKCLSVGMS RDAVRFGRIP KREKQRMLAE MQSAMNLANN QLSSQCPLET SPTQHPTPGP MGPSPPPAPV PSPLVGFSQF PQQLTPPRSP SPEPTVEDVI SQVARAHREI FTYAHDKLGS SPGNFNANHA SGSPPATTPH RWENQGCPPA PNDNNTLAAQ R (1-350 aa encoded by BC056148)
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BD73; EAR-1; nuclear receptor protein; nuclear receptor Rev-ErbA-alpha; Nuclear receptor subfamily 1 group D member 1; nuclear receptor subfamily 1, group D, member 1; orphan nuclear receptor; rev-erb alpha; Rev-erba; rev-erbA alpha; rev-erbA(alpha); Rev-erbA-alpha; Rev-ErbA-alpha protein; Rev-ErbAalpha; REV-ERBalpha; Reverbaalpha; V-erbA-related protein 1
Gene Aliases: A530070C09Rik; ear-1; EAR1; HREV; NR1D1; R75201; THRA1; THRAL
UniProt ID: (Human) P20393, (Mouse) Q3UV55
Entrez Gene ID: (Human) 9572, (Mouse) 217166
Molecular Function:
C4 zinc finger nuclear receptor
DNA-binding transcription factor
zinc finger transcription factor
gene-specific transcriptional regulator
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