Recommended positive controls: Human NR1D1-transfected 293T cells.
Predicted reactivity: Mouse (93%), Rat (93%), Sheep (92%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
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Protein Aliases: BD73; EAR-1; nuclear receptor protein; nuclear receptor Rev-ErbA-alpha; Nuclear receptor subfamily 1 group D member 1; nuclear receptor subfamily 1, group D, member 1; orphan nuclear receptor; rev-erb alpha; Rev-erba; rev-erbA alpha; rev-erbA(alpha); Rev-erbA-alpha; Rev-ErbA-alpha protein; Rev-ErbAalpha; REV-ERBalpha; Reverbaalpha; V-erbA-related protein 1
Gene Aliases: A530070C09Rik; ear-1; EAR1; HREV; NR1D1; R75201; THRA1; THRAL