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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • NREP Antibodies

          Invitrogen

          NREP Polyclonal Antibody

          1 Reference
          View all (4) NREP antibodies

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          Cite NREP Polyclonal Antibody

          • Antibody Testing Data (3)
          NREP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          NREP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          NREP Antibody (PA5-68426) in IHC (P)

          Immunohistochemical analysis of NREP in paraffin-embedded Human esophagus cancer tissue using (left) NREP Polyclonal Antibody (Product # PA5-68426) at a 1:25 dilution and (right) is treated with synthetic peptide. (Original magnification: x200). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NREP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NREP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NREP Antibody in Western Blot (WB)

          Product Details

          PA5-68426

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200-1:1,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:100
          -
          Product Specifications

          Species Reactivity

          Human

          Published species

          C. elegans

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthesized peptide derived from human NREP.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 40% glycerol

          Contains

          0.05% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2692062

          Target Information

          P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.1.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Neuronal protein 3.1; neuronal regeneration related protein homolog; Neuronal regeneration-related protein; Protein p311

          View more View less

          Gene Aliases: C5orf13; D4S114; NREP; P311; PRO1873; PTZ17; SEZ17

          View more View less

          UniProt ID: (Human) Q16612

          View more View less

          Entrez Gene ID: (Human) 9315

          View more View less

          Function(s)
          protein binding
          Process(es)
          regulation of transforming growth factor beta receptor signaling pathway axon regeneration regulation of neuron differentiation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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