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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthetic peptide corresponding to amino acids 50-115 of human NRG4. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.74 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2807986 |
Immunogen sequence: MPTDHEEPCG PSHKSFCLNG GLCYVIPTIP SPFCRCVENY TGARCEEVFL PGSSIQTKSN LFEAFVALAV LVTLIIGAFY FLCRKGHFQR ASSVQYDINL VETSSTSAHH SHEQH; Cellular Location: Cell membrane, Single-pass type I membrane protein
The neuregulins, including NRG4, activate type-1 growth factor receptors to initiating cell-to-cell signaling through tyrosine phosphorylation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: heregulin 4; Neuregulin-4; NRG-4; Pro-neuregulin-4, membrane-bound isoform; Pro-NRG4
Gene Aliases: AI552600; HRG4; NRG4
UniProt ID: (Human) Q8WWG1, (Mouse) Q9WTX4
Entrez Gene ID: (Human) 145957, (Mouse) 83961, (Rat) 690919
Molecular Function:
growth factor
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