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Product Details
15111-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,200 | View 3 publications 3 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Immunohistochemistry (IHC) |
- | View 3 publications 3 publications |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
NSDHL Fusion Protein Ag7097 (1-303 aa encoded by BC000245) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.39 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MEPAVSEPM RDQVARTHLT EDTPKVNADI EKVNQNQAKR CTVIGGSGFL GQHMVEQLLA RGYAVNVFDI QQGFDNPQVR FFLGDLCSRQ DLYPALKGVN TVFHCASPPP SSNNKELFYR VNYIGTKNVI ETCKEAGVQK LILTSSASVI FEGVDIKNGT EDLPYAMKPI DYYTETKILQ ERAVLGANDP EKNFLTTAIR PHGIFGPRDP QLVPILIEAA RNGKMKFVIG NGKNLVDFTF VENVVHGHIL AAEQLSRDST LGGKAFHITN DEPIPFWTFL SRILTGLNYE APKYHIPYWV AYYL (1-303 aa encoded by BC000245)
Target Information
The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bare patches; NAD(P)-dependent steroid dehydrogenase-like protein; Protein H105e3; short chain dehydrogenase/reductase family 31E, member 1; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; striated
Gene Aliases: AI747449; Bpa; H105E3; NSDHL; SDR31E1; Str; XAP104
UniProt ID: (Human) Q15738, (Mouse) Q9R1J0, (Rat) Q5PPL3
Entrez Gene ID: (Human) 50814, (Mouse) 18194, (Rat) 309262
Molecular Function:
dehydratase
hair follicle development
cholesterol biosynthetic process
smoothened signaling pathway
oxidation-reduction process
labyrinthine layer blood vessel development
lipid metabolic process
steroid biosynthetic process
steroid metabolic process
cholesterol metabolic process
sterol biosynthetic process
biological_process
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
3-beta-hydroxy-delta5-steroid dehydrogenase activity
sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
molecular_function
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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