This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: LPYAMKPIDY YTETKILQER AVLGANDPEK NFLTTAIRPH GIFGPRDPQL VPILIEAARN GKMKFVIGNG KNLVDFTFVE NVVHGHILAA EQLSRDSTLG GKAFHITNDE PIPFWTFLSR I
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bare patches; NAD(P)-dependent steroid dehydrogenase-like protein; Protein H105e3; short chain dehydrogenase/reductase family 31E, member 1; Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; striated
Gene Aliases: AI747449; Bpa; H105E3; NSDHL; SDR31E1; Str; XAP104
Molecular Function: dehydratase