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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant human NT-4|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Functional Assay (FN)||Assay-dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-33002 detects NT4 from human samples.
PA1-33002 has been successfully used in Western blot applications.
The PA1-33002 immunogen is: Recombinant human NT-4
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
neurotrophic factor 4; neurotrophic factor 5; neurotrophin 5 (neurotrophin 4/5); neurotrophin-4; neurotrophin-5; neutrophic factor 4
GLC10; GLC1O; NT-4; NT-4/5; NT-5; NT4; NT5; NTF5
Signal transduction Cell surface receptor mediated signal transduction Receptor protein tyrosine kinase signaling pathway Cell communication Ligand-mediated signaling Developmental processes Ectoderm development Neurogenesis