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Invitrogen
NT5C2 Polyclonal Antibody
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Product Details
PA5-103777
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NT5C2(Accession P49902), corresponding to amino acid residues F389-S439.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total NT5C2.
Target Information
Purine 5-prime-nucleotidase (EC 3.1.3.5) preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine nucleotides, and is allosterically activated by various compounds, including ATP. The enzyme is exclusively located in the cytoplasmic matrix of cells and may have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-nucleotidase (purine), cytosolic type B; cN-II; Cytosolic 5'-nucleotidase II; Cytosolic IMP/GMP-specific 5'-nucleotidase; Cytosolic nucleoside phosphotransferase 5'N; Cytosolic purine 5'-nucleotidase; epididymis secretory sperm binding protein; High Km 5'-nucleotidase; IMP-specific 5'-NT; RP11-30H12.3; spastic paraplegia 45 (autosomal recessive); unnamed protein product
Gene Aliases: 2010002I23Rik; cN-II; CnII; ENSMUSG00000025039; Gm9751; GMP; NT5B; NT5C2; NT5CP; PNT5; SPG45; SPG65
UniProt ID: (Human) P49902, (Mouse) Q3V1L4
Entrez Gene ID: (Human) 22978, (Mouse) 76952
allantoin metabolic process
GMP catabolic process to guanine
IMP catabolic process
nucleotide metabolic process
cellular amide catabolic process
GMP metabolic process
GMP catabolic process
IMP metabolic process
dGMP metabolic process
dGMP catabolic process
adenosine metabolic process
negative regulation of defense response to virus by host
protein K48-linked ubiquitination
antiviral innate immune response
metabolic process
dephosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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