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Proteintech

NT5M Polyclonal Antibody

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NT5M Polyclonal Antibody

Product Details

20765-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

NT5M Fusion Protein Ag14743 (36-228 aa encoded by BC035838)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.44 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LRVLVDMDG VLADFEGGFL RKFRARFPDQ PFIALEDRRG FWVSEQYGRL RPGLSEKAIS IWESKNFFFE LEPLPGAVEA VKEMASLQNT DVFICTSPIK MFKYCPYEKY AWVEKYFGPD FLEQIVLTRD KTVVSADLLI DDRPDITGAE PTPSWEHVLF TACHNQHLQL QPPRRRLHSW ADDWKAILDS KRPC (36-228 aa encoded by BC035838)

Target Information

Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 5' nucleotidase, mitochondrial; 5'(3')-deoxyribonucleotidase, mitochondrial; 5',3'-deoxyribonucleotidase, mitochondrial; 5',3'-nucleotidase, mitochondrial; 5(3)-deoxyribonucleotidase; Deoxy-5'-nucleotidase 2; dNT-2; mitochondrial 5' nucleotidase

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Gene Aliases: 2010013E09Rik; AI846937; dNT-2; DNT2; mdN; NT5M

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UniProt ID: (Human) Q9NPB1, (Mouse) Q8VCE6

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Entrez Gene ID: (Human) 56953, (Rat) 287368, (Mouse) 103850

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Function(s)
nucleotide binding nucleotidase activity 5'-nucleotidase activity metal ion binding protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity phosphohistidine phosphatase activity inositol bisphosphate phosphatase activity hydrolase activity MAP kinase tyrosine/serine/threonine phosphatase activity inositol-1,3,4-trisphosphate 4-phosphatase activity NADP phosphatase activity transmembrane receptor protein phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity inositol-4,5-bisphosphate 5-phosphatase activity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity phosphatidylinositol-4-phosphate phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity inositol phosphate phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity inositol-3,4-bisphosphate 4-phosphatase activity inositol-1,3,4-trisphosphate 1-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity IDP phosphatase activity
Process(es)
DNA replication pyrimidine deoxyribonucleotide catabolic process dephosphorylation dUMP catabolic process pyrimidine nucleoside catabolic process nucleotide metabolic process deoxyribonucleotide catabolic process
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