|Tested species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant mouse NTAL (aa 30-203).|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay Dependent|
|Western Blot (WB)||1 ug/ml|
This antibody will not cross-react with human.
NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
LAB; LAT-2 like; linker for activation of B-cells; linker for activation of T-cells family member 2; membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein
AW125574; LAB; Lat2; NTAL; Wbscr15; Wbscr5; WSCR5