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Invitrogen
NTN1 Polyclonal Antibody
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Product Details
PA5-95038
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Netrin 1 (32-51aa AGQAAQPDPCSDENGHPRRC).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: U87 Cell, COLO320 Cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Netrin-1 is a protein target that plays a crucial role in various biological processes, particularly in the development and guidance of neuronal cells. It belongs to the netrin family of axon guidance molecules and is involved in mediating axon guidance, cell migration, and tissue morphogenesis during embryonic development. Netrin-1 functions by binding to specific receptors on the cell surface and providing directional cues for cellular movement and connectivity. Dysregulation of Netrin-1 has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular conditions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Epididymis tissue protein Li 131P; HGNC:8029; netrin 1, mouse, homolog of; Netrin-1; Netrin1
Gene Aliases: AI561871; BC019633; Netrin-1; NTN1; NTN1L
UniProt ID: (Human) O95631, (Mouse) O09118
Entrez Gene ID: (Human) 9423, (Mouse) 18208, (Rat) 114523
neuron migration
apoptotic process
substrate-dependent cell migration, cell extension
Ras protein signal transduction
axon guidance
positive regulation of cell proliferation
single organismal cell-cell adhesion
regulation of cell migration
negative regulation of axon extension
Cdc42 protein signal transduction
anterior/posterior axon guidance
establishment of nucleus localization
inner ear morphogenesis
positive regulation of axon extension
mammary gland duct morphogenesis
positive regulation of cell motility
axonogenesis
mammary gland development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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