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Invitrogen
NTN1 Polyclonal Antibody
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FIGURE: 1 / 2
NTN1 Antibody (PA5-98017) in IHC (P)
Immunohistochemical analysis of NTN1 in paraffin embedded human liver tissue using a NTN1 polyclonal antibody (Product # PA5-98017) at a dilution of 1:400. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected... View More
Product Details
PA5-98017
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Netrin-1 protein (186-478AA)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Netrin-1 is a protein target that plays a crucial role in various biological processes, particularly in the development and guidance of neuronal cells. It belongs to the netrin family of axon guidance molecules and is involved in mediating axon guidance, cell migration, and tissue morphogenesis during embryonic development. Netrin-1 functions by binding to specific receptors on the cell surface and providing directional cues for cellular movement and connectivity. Dysregulation of Netrin-1 has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Epididymis tissue protein Li 131P; HGNC:8029; netrin 1, mouse, homolog of; Netrin-1; Netrin1
Gene Aliases: MRMV4; NET1; NTN1; NTN1L
UniProt ID: (Human) O95631
Entrez Gene ID: (Human) 9423
neuron migration
regulation of transcription from RNA polymerase II promoter
apoptotic process
substrate-dependent cell migration, cell extension
nuclear migration
Ras protein signal transduction
axonogenesis
axon guidance
cell proliferation
glial cell proliferation
regulation of cell migration
negative regulation of axon extension
mammary gland development
Cdc42 protein signal transduction
anterior/posterior axon guidance
inner ear morphogenesis
positive regulation of axon extension
regulation of synapse assembly
positive regulation of glial cell proliferation
mammary gland duct morphogenesis
chemorepulsion of axon
motor neuron migration
cell-cell adhesion
regulation of glial cell migration
positive regulation of cell motility
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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