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Proteintech
NUS1 Polyclonal Antibody
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Product Details
15986-1-AP
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NUS1 Fusion Protein Ag8789 (1-293 aa encoded by BC013026)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Amount
73.5 µg
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTGLYELVW RVLHALLCLH RTLTSWLRVR FGTWNWIWRR CCRAASAAVL APLGFTLRKP PAVGRNRRHH RHPRGGSCLA AAHHRMRWRA DGRSLEKLPV HMGLVITEVE QEPSFSDIAS LVVWCMAVGI SYISVYDHQG IFKRNNSRLM DEILKQQQEL LGLDCSKYSP EFANSNDKDD QVLNCHLAVK VLSPEDGKAD IVRAAQDFCQ LVAQKQKRPT DLDVDTLASL LSSNGCPDPD LVLKFGPVDS TLGFLPWHIR LTEIVSLPSH LNISYEDFFS ALRQYAACEQ RLGK (1-293 aa encoded by BC013026)
Target Information
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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