Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: NPAGIPHFVH RELKSEKVEQ IKLAMNQQCD VSQEALDIQR LPFYPDMVNR DTKMASNPRK CMAASLDVHE ENIPTVMSAG EMDKWKGIEP GEKCADRSPV CTTFSDTSSN INSILELFPK LLCLDGQQSP RATLCGTEAH KRL
Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 41%.
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Nuclear RNA export factor 3; TAP-like protein 3; TAPL-3
Gene Aliases: NXF3; TAPL3
UniProt ID: (Human) Q9H4D5
Entrez Gene ID: (Human) 56000
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support