Immunogen sequence: QNEPRIVTSE EVIIRDSPVL PVTLQCNLTS SSHTLTYSYW TKNGVELSAT RKNASNMEYR INKPRAEDSG EYHCVYHFVS APKANATIEV KAAPDITGHK RSENKNEGQD ATMYCKSVGY PHPDWIWRKK ENGMPMDIVN TSGRFFIINK ENYTELNIVN LQITEDPGEY EC; Positive Samples: SKOV3, Jurkat; Cellular Location: Cell membrane, Single-pass type I membrane protein
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
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Protein Aliases: glycoprotein 55; Glycoprotein 55/65; glycoprotein 65; gp55/65; Neuroplastin; SDR-1; stromal cell derived factor receptor 1; Stromal cell-derived receptor 1
Gene Aliases: AW554172; GP55; GP65; np55; np65; NPTN; SDFR1; SDR-1; SDR1
Molecular Function: transmembrane receptor regulatory/adaptor protein