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Invitrogen
Nudel Polyclonal Antibody
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Product Details
PA5-19082
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (CRNFAKDQASRKSY) corresponding to the internal amino acids of NDEL1 (aa 273-287).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp451M0318; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; Nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein Nudel
Gene Aliases: EOPA; MITAP1; NDE1L1; NDE2; NDEL1; NUDEL
UniProt ID: (Human) Q9GZM8
Entrez Gene ID: (Human) 81565
establishment of mitotic spindle orientation
neuron migration
inner cell mass cell proliferation
proteolysis
microtubule nucleation
chromosome segregation
sister chromatid cohesion
mitotic centrosome separation
retrograde axonal transport
regulation of neuron projection development
cell migration
cerebral cortex radially oriented cell migration
central nervous system neuron axonogenesis
regulation of intracellular protein transport
positive regulation of GTPase activity
positive regulation of axon extension
vesicle transport along microtubule
positive regulation of axon regeneration
nuclear envelope disassembly
establishment of chromosome localization
centrosome localization
neurofilament cytoskeleton organization
activation of GTPase activity
neuron projection extension
regulation of microtubule motor activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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