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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
OAZ1 catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. This protein play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein expression is auto-regulated by polyamine-enhanced translational frameshifting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: antizyme 1; AZ1; ODC-Az; Ornithine decarboxylase antizyme 1
Gene Aliases: Antizyme; AZ-1; AZ1; AZI; OAZ; OAZ1; ODC-Az; ODCAC
UniProt ID: (Human) O43382, (Mouse) P54369, (Rat) P54370
Entrez Gene ID: (Human) 4946, (Mouse) 18245, (Rat) 25502
Molecular Function:
protein-binding activity modulator
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