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Proteintech
ONECUT2 Polyclonal Antibody
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Product Details
21916-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ONECUT2 Fusion Protein Ag16162 (226-332 aa encoded by BC108925)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PLAATPLGN GLGGLHNAQQ SLPNYGPPGH DKMLSPNFDA HHTAMLTRGE QHLSRGLGTP PAAMMSHLNG LHHPGHTQSH GPVLAPSRER PPSSSSGSQV ATSGQLEE (226-332 aa encoded by BC108925)
Target Information
ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Hepatocyte nuclear factor 6-beta; HNF-6-beta; HNF-6B; OC-2; One cut domain family member 2; One cut homeobox 2; onecut 2; ONECUT-2 homeodomain transcription factor; Transcription factor ONECUT-2; transcription factor ONECUT2
Gene Aliases: C730009D12; HNF6B; OC-2; OC2; ONECUT2
UniProt ID: (Human) O95948, (Mouse) Q6XBJ3
Entrez Gene ID: (Human) 9480, (Mouse) 225631
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
homeodomain transcription factor
liver development
regulation of cell-matrix adhesion
epithelial cell development
regulation of transcription from RNA polymerase II promoter
transforming growth factor beta receptor signaling pathway
anatomical structure morphogenesis
organ morphogenesis
cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
pancreas development
endocrine pancreas development
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
peripheral nervous system neuron development
cilium morphogenesis
mesenchymal stem cell migration
positive regulation of mesenchymal stem cell migration
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell differentiation
positive regulation of cell migration
cilium assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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