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PA1-32851 detects OPRD1 from human samples.
OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D-OR-1; delta opioid receptor 1; Delta-type opioid receptor; DOR-1; Opioid receptor; opioid receptor, delta 1
Gene Aliases: OPRD; OPRD1
UniProt ID: (Human) P41143
Entrez Gene ID: (Human) 4985