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Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000 | View 4 publications 4 publications |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunocytochemistry (ICC/IF) |
1:250 | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Mouse, Rat |
Published species |
Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
The antiserum was produced against a chemically synthesized peptide derived from the internal region of the mouse k-opioid receptor. The sequence is conserved in rat. |
Conjugate |
Unconjugated |
Form |
Liquid |
Purification |
Antigen affinity chromatography |
Storage buffer |
Dulbecco's PBS, pH 7.3, with 50% glycerol, 1mg/mL BSA |
Contains |
0.05% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2533627 |
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: K-OR-1; Kappa-type opioid receptor; KOPR1; KOR-1; MSL-1; opioid receptor, kappa 2; Ork1
Gene Aliases: K-OR-1; KOR; KOR-1; MSL-1; Oprk1; Oprk2; R21; Ror-d
UniProt ID: (Mouse) P33534, (Rat) P34975
Entrez Gene ID: (Mouse) 18387, (Rat) 29335
Molecular Function:
G-protein coupled receptor
transmembrane signal receptor
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