Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
ORAI3 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-20370
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 15 amino acid peptide from near the amino terminus of human ORAI3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is A-20 cell lysate.
PA5-2037° Can be used with blocking peptide PEP-0487.
Target Information
ORAI3 is a protein coding gene that is involved in calcium signaling and regulation of calcium homeostasis. It is a member of the ORAI family of proteins that form calcium release-activated calcium (CRAC) channels in the plasma membrane of cells. These channels are activated by depletion of calcium from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm. ORAI3 has been implicated in a variety of physiological processes, including T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function has been associated with various diseases, including immune disorders, cancer, and cardiovascular disease
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcium release-activated calcium channel 3; calcium release-activated calcium modulator 3 protein; Protein orai-3; Transmembrane protein 142C
Gene Aliases: 9930124N15; BC061259; ORAI3; RGD1306538; TMEM142C
UniProt ID: (Human) Q9BRQ5, (Mouse) Q6P8G8, (Rat) Q6AXR8
Entrez Gene ID: (Human) 93129, (Mouse) 269999, (Rat) 309000
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support