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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ORC2 Antibodies

          Invitrogen

          ORC2 Polyclonal Antibody

          Advanced Verification
          1 Reference
          View all (10) ORC2 antibodies

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          Cite ORC2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (8)
          • Advanced Verification (1)
          ORC2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          ORC2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 9

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          ORC2 Antibody (PA5-67313) in ICC/IF

          Immunofluorescence analysis of ORC2 was performed using HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with ORC2 Monoclonal Antibody (Product # PA5-67313) at 1:200 dilution in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at 1:2000 dilution for 45 minutes... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          ORC2 Antibody in Immunocytochemistry (ICC/IF)
          ORC2 Antibody in Immunocytochemistry (ICC/IF)
          ORC2 Antibody in Western Blot (WB)
          ORC2 Antibody in Western Blot (WB)
          ORC2 Antibody in Western Blot (WB)
          ORC2 Antibody in ChIP Assay (ChIP)
          ORC2 Antibody in ChIP Assay (ChIP)
          ORC2 Antibody in ChIP Assay (ChIP)
          ORC2 Antibody
          ORC2 Polyclonal Antibody

          Product Details

          PA5-67313

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -

          ChIP assay (ChIP)

          1-10 µg
          -
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human ORC2. Recombinant protein control fragment (Product #RP-105586).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.30 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2663245

          Product Specific Information

          Immunogen sequence: MLEVHFVGDDD VLNHILDREG GAKLKKERAQ LLVNPKKIIK KPEYDLEEDD QEVLKDQNYV EIMGRDVQES LKNGSATGGG NKVYSFQNRK HSEKMAK

          Highest antigen sequence identity to the following orthologs - mouse 69%, rat 70%.

          Target Information

          The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: origin recognition complex protein 2 homolog; Origin recognition complex subunit 2; origin recognition complex, subunit 2 homolog

          View more View less

          Gene Aliases: ORC2; ORC2L

          View more View less

          UniProt ID: (Human) Q13416

          View more View less

          Entrez Gene ID: (Human) 4999

          View more View less

          Function(s)
          DNA replication origin binding protein binding replication origin binding protein
          Process(es)
          G1/S transition of mitotic cell cycle negative regulation of transcription from RNA polymerase II promoter DNA replication DNA replication initiation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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