The recommended shelf life for this product is 1 year from date of receipt.
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ORC6; ORC6L; Origin recognition complex subunit 6; origin recognition complex, subunit 6 (yeast homolog)-like; origin recognition complex, subunit 6 homolog-like (yeast); origin recognition complex, subunit 6-like (yeast)
Gene Aliases: ORC6; ORC6L
UniProt ID: (Human) Q9Y5N6
Entrez Gene ID: (Human) 23594