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Proteintech
ORM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
11199-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ORM2 Fusion Protein Ag1667 (1-201 aa encoded by BC015964)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.45 mg/mL
Amount
67.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize both ORM1 and ORM2.
Immunogen sequence: MALSWVLTV LSLLPLLEAQ IPLCANLVPV PITNATLDRI TGKWFYIASA FRNEEYNKSV QEIQATFFYF TPNKTEDTIF LREYQTRQNQ CFYNSSYLNV QRENGTVSRY EGGREHVAHL LFLRDTKTLM FGSYLDDEKN WGLSFYADKP ETTKEQLGEF YEALDCLCIP RSDVMYTDWK KDKCEPLEKQ HEKERKQEEG ES (1-201 aa encoded by BC015964)
Target Information
AGP (a 1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/mL, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP-1, AGP-2, AGP-3 and AGP-8. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AGP 2; alpha-1-acid glycoprotein; alpha-1-acid glycoprotein, type 2; bM340H1.5 (orosomucoid 2); OMD 2; OMD2; ORM2; Orosomucoid2; unnamed protein product
Gene Aliases: AGP-B; AGP-B'; Agp1; AGP2; Orm-2
UniProt ID: (Human) P19652, (Mouse) P07361
Entrez Gene ID: (Human) 5005, (Mouse) 18406
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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