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Proteintech
OSMR Polyclonal Antibody
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Product Details
10982-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OSMR Fusion Protein Ag1426 (1-342 aa encoded by BC010943)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MALFAVFQT TFFLTLLSLR TYQSEVLAER LPLTPVSLKV STNSTRQSLH LQWTVHNLPY HQELKMVFQI QISRIETSNV IWVGNYSTTV KWNQVLHWSW ESELPLECAT HFVRIKSLVD DAKFPEPNFW SNWSSWEEVS VQDSTGQDIL FVFPKDKLVE EGTNVTICYV SRNIQNNVSC YLEGKQIHGE QLDPHVTAFN LNSVPFIRNK GTNIYCEASQ GNVSEGMKGI VLFVSKVLEE PKDFSCETED FKTLHCTWDP GTDTALGWSK QPSQSYTLFE SFSGEKKLCT HKNWCNWQIT QDSQETYNFT LIAENYLRKR SVNILFNLTH RGETRVVTAH RGH (1-342 aa encoded by BC010943)
Target Information
Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: IL-31 receptor subunit beta; IL-31R subunit beta; Interleukin-31 receptor subunit beta; MGC150626; MGC150627; MGC75127; oncostatin-M specific receptor beta subunit; Oncostatin-M-specific receptor subunit beta
Gene Aliases: IL-31R-beta; IL-31RB; OSMR; OSMRB; PLCA1
UniProt ID: (Human) Q99650
Entrez Gene ID: (Human) 9180
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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