Reconstitute with 500 µL of distilled water.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
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Protein Aliases: 3010009O07Rik; AI115608; capacitative calcium entry channel; membe; mTrp2; smTRPC2; transient receptor potential protein; TRP-1 protein; trp2; TRPC2a; TRPC2b; Trrp2
Gene Aliases: trp; trpc1; XELAEV_18027727mg; xtrpc1
Entrez Gene ID: (Xenopus) 399136