Recommended positive controls: A431, HepG2, mouse Liver.
Predicted reactivity: Mouse (94%), Rat (93%), Pig (94%), Chicken (80%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; OTCase; sparse fur
Gene Aliases: AI265390; OCTD; OTC; Sf; spf